
Center for Archaeological Science, Sichuan University published in top forensic science journal FSIG, reporting that global population non-CODIS STR profiles provide new ideas for forensic complex DNA analysis
Short tandem repeats (STRs) account for approximately 6% of the genome and are a class of highly polymorphic genetic markers. Since their first application in forensic DNA analysis in the 1990s, STRs have played an important role in population genetics research, personal identification, biogeographic ancestry inference, parentage testing, and kinship analysis. Currently, mainstream STR detection kits generally contain only 20-30 STR markers, including the core loci of the FBI Combined DNA Index System (CODIS), which are difficult to meet the increasingly complex needs of forensic DNA analysis. High-throughput next-generation sequencing technology...